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"Madhouse" is a single by thrash metal band Anthrax, from the album, Spreading the Disease. The song is an up-tempo song with hard riffs and contains one of the strongest thrash tempos Anthrax has created in their early time. The song has become a staple of live concerts, and has also appeared on Anthrax's "best of" album, Anthrology: No Hit Wonders (1985-1991).
It is included in the 2002 video game Grand Theft Auto: Vice City, on the fictional radio station V-Rock. It is also featured in the PlayStation 2 and Xbox 360 video game, Guitar Hero II.
In 2009 it was named the 46th best hard rock song of all time by VH1.

A music video was produced for this song as well, but didn't receive much airplay due to the fact that it was banned by MTV, who believed the content to be degrading to the mentally ill.

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