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According to the Take It Off Songfacts Ke$ha is fascinated by transvestites and this song is about when she went to a drag show, and got turned on by the transvestite men taking clothes off.

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There's a place downtown,
Where the freaks all come around
It's a hole in the wall, it's a dirty free for all

When the dark of the night comes…

Ke$ha - Take It Off Lyrics


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