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Billie Joe Armstrong told Q magazine : "It's about pharmaceuticals. A lot of people become junkies if they get the right prescription." (Source Restless Heart Syndrome Songfacts).

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I've got a really bad disease
It's got me begging
On my hands and knees
So take me to the emergency
Cause something seems to be missing
Somebody take…

Green Day - Restless Heart Syndrome Lyrics

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