This song is about drugs, especially marijuana. A "Toke" is a puff from a marijuana cigarette or pipe. Tom Shipley explained: "When we wrote 'One Toke Over the Line,' I think we were one toke over the line. I considered marijuana a sort of a sacrament... If you listen to the lyrics of that song, 'one toke' was just a metaphor. It's a song about excess. Too much of anything will probably kill you."