OK so I got a Bamboo graphics tablet recently. Since then, iScrobbler crashes. A lot. And I see references to Ink in the crash dump, so I wondered whether the things are related... I can't see why they would be, but anyway.
It worked on and off for a while, but right now I can't even start iScrobbler, it crashes on startup. NB the tablet is not plugged in.
Incompatibilities
In addition to Cocoa Gestures, the Logitech Control Center 2.4 driver software causes problems with Growl and may also cause iPod handling problems in iScrobbler.
Apple's Ink service has a bug in 10.5.x that causes 64bit apps to crash. Either disable Ink or use the 32bit version of iScrobbler.
Weird crashes - graphics tablet / ink related?